Figure 2.

Immunostain for TGF-β1 antibody (DAB, ×200) of infected untreated liver sections of mice killed 10 (a) and 18 (b) weeks PI showing marked positively stained hepatocytes and granuloma (fibroblast and inflammatory cells; arrows). Sections taken from livers of mice treated with PZQ (500 mg/kg/day for 2 days) showing mild (a) and moderate (b) positively stained hepatocytes, endothelial cells lining sinusoids and granuloma cells (arrows). Sections taken from livers of mice treated with silymarin (750 mg/kg/day, 5 days/week for 6 weeks) showing weak (a) and moderate (b) positively stained hepatocytes, endothelial cells lining sinusoids and granuloma cells (arrows). Sections taken from livers of mice treated with PZQ plus silymarin showing weakly and scattered positively stained hepatocytes and granuloma cells (a, b; arrows).

El-Lakkany et al. Parasites & Vectors 2012 5:9   doi:10.1186/1756-3305-5-9
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