Onchocerciasis Control: Vision for the Future from a Ghanian perspective

doi:10.1186/1756-3305-2-7

Parasites & Vectors

Volume 2

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Taylor MJ
Awadzi K
Basáñez MG
Biritwum N
Boakye D
Boatin B
Bockarie M
Churcher TS
Debrah A
Edwards G
Hoerauf A
Mand S
Matthews G
Osei-Atweneboana M
Prichard RK
Wanji S
Adjei O

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Taylor MJ
Awadzi K
Basáñez MG
Biritwum N
Boakye D
Boatin B
Bockarie M
Churcher TS
Debrah A
Edwards G
Hoerauf A
Mand S
Matthews G
Osei-Atweneboana M
Prichard RK
Wanji S
Adjei O
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Meeting report

Onchocerciasis Control: Vision for the Future from a Ghanian perspective

Mark J Taylor¹ , Kwablah Awadzi² , María-Gloria Basáñez³ , Nana Biritwum⁴ , Daniel Boakye⁵ , Boakye Boatin⁶ , Moses Bockarie⁷ , Thomas S Churcher³ , Alex Debrah⁸ , Geoffrey Edwards¹ , Achim Hoerauf⁹ , Sabine Mand⁹ , Graham Matthews¹⁰ , Mike Osei-Atweneboana¹¹ , Roger K Prichard¹¹ , Samuel Wanji¹² and Ohene Adjei⁸

¹Molecular and Biochemical Parasitology, Liverpool School of Tropical Medicine, Liverpool, UK

²Onchocerciasis Chemotherapy Research Centre (OCRC), Hohoe Hospital, Hohoe, Ghana

³Department of Infectious Disease Epidemiology, Imperial College, London, UK

⁴Lymphatic Filariasis Elimination Programme, Health Research Unit, Ghana Health Service, Accra, Ghana

⁵Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Accra, Ghana

⁶TDR, World Health Organisation, Geneva, Switzerland

⁷Centre for Neglected Tropical Diseases (incorporating the Lymphatic Filariasis Support Centre), Liverpool School of Tropical Medicine, Liverpool, UK

⁸Kumasi Centre for Collaborative Research (KCCR), Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana

⁹Institute for Medical Microbiology, Immunology & Parasitology, University of Bonn, Bonn, Germany

¹⁰Department of Biological Sciences, Imperial College of Science, Technology and Medicine, London, UK

¹¹Institute of Parasitology, McGill University, Québec, Canada

¹²Research Foundation for Tropical Diseases and the Environment (REFOTDE), Buea, Cameroon

author email corresponding author email

Parasites & Vectors 2009, 2:7doi:10.1186/1756-3305-2-7


Published:	21 January 2009

Abstract

Since 1987 onchocerciasis control has relied on the donation of ivermectin (Mectizan^®, Merck & Co., Inc.) through the Mectizan Donation Programme. Recently, concern has been raised over the appearance of suboptimal responses to ivermectin in Ghana – highlighting the potential threat of the development of resistance to ivermectin. This report summarises a meeting held in Ghana to set the research agenda for future onchocerciasis control. The aim of this workshop was to define the research priorities for alternative drug and treatment regimes and control strategies to treat populations with existing evidence of suboptimal responsiveness and define research priorities for future control strategies in the event of the development of widespread ivermectin resistance.