Community-directed delivery of doxycycline for the treatment of onchocerciasis in areas of co-endemicity with loiasis in Cameroon
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* Corresponding author: Samuel Wanji swanji@yahoo.fr
Parasites & Vectors 2009, 2:39 doi:10.1186/1756-3305-2-39
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BioMed Central: 5 citations
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Short report
Francesca Tamarozzi, Nicholas Tendongfor, Peter A Enyong, Mathias Esum, Brian Faragher, Samuel Wanji, Mark J Taylor Parasites & Vectors 2012, 5:53 (20 March 2012) This study demonstrates the long-term effectiveness of doxycycline treatment delivered with a community-directed strategy even when evaluated four years after delivery in an area of ongoing transmission. This finding shows that community-delivery of doxycycline is feasible, safe and effective for the control and treatment of onchocerciasis in areas co-endemic for Loa loa. Image: Adult female Onchocerca volvulus.
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Research
Effects of Doxycycline on gene expression in Wolbachia and Brugia malayi adult female worms in vivo Ramakrishna U Rao, Yuefang Huang, Sahar Abubucker, Michael Heinz, Seth D Crosby, Makedonka Mitreva, Gary J Weil Journal of Biomedical Science 2012, 19:21 (9 February 2012) |
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Research
Anna Albers, Mathias Esum, Nicholas Tendongfor, Peter Enyong, Ute Klarmann, Samuel Wanji, Achim Hoerauf, Kenneth Pfarr Parasites & Vectors 2012, 5:12 (11 January 2012) Depleting Wolbachia essential endosymbionts from Onchocerca volvulus led to fewer third-stage larvae developing in the Simulium blackfly vector required for development and disease transmission.
Image: Fewer third-stage larvae (light gray bars) are recovered from blackflies that have fed on Onchocerca volvulus infected volunteers.
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Review
Onchocerciasis in the Americas: from arrival to (near) elimination Ken Gustavsen, Adrian Hopkins, Mauricio Sauerbrey Parasites & Vectors 2011, 4:205 (25 October 2011) This article is part of a collection on Elimination of parasitic... Onchocerciasis (river blindness) is a public health threat for millions worldwide. This article charts the course of onchocerciasis in the Western Hemisphere and discusses the prospects for elimination of the disease. Image: Using a dose pole to determine the correct dosage for onchocerciasis treatment.
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Research
Joseph C Okeibunor, Bright C Orji, William Brieger, Gbenga Ishola, Emmanuel Otolorin, Barbara Rawlins, Enobong U Ndekhedehe, Nkechi Onyeneho, Günther Fink Malaria Journal 2011, 10:227 (5 August 2011) Given the relatively modest financial commitments they require, community-directed programmes appear to be a cost-effective way to improve malaria prevention
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