Parasites & Vectors

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The history of African trypanosomiasis

Dietmar Steverding

Parasites & Vectors 2008, 1:3 doi:10.1186/1756-3305-1-3

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BioMed Central: 4 citations

Research article   Open Access Highly Accessed

Biochemical characterization of trans-sialidase TS1 variants from Trypanosoma congolense

Hendrik Koliwer-Brandl, Thaddeus T Gbem, Mario Waespy, Olga Reichert, Philipp Mandel, Eric Drebitz, Frank Dietz, Sørge Kelm BMC Biochemistry 2011, 12:39 (30 July 2011)

Review   Open Access Highly Accessed

The development of drugs for treatment of sleeping sickness: a historical review

Dietmar Steverding Parasites & Vectors 2010, 3:15 (10 March 2010)

This article is part of a collection on Historical aspects of...

This review article outlines the development of anti-sleeping sickness drugs from the discovery of the first bioactive lead compounds to the identification of more modern chemotherapeutic agents. Image: Paul Ehrlich, pioneer in the development of drugs against trypanosomes.

Editorial   Open Access Highly Accessed

'ONE HEALTH' and parasitology

Bruce Kaplan, Laura H Kahn, Thomas P Monath, Jack Woodall Parasites & Vectors 2009, 2:36 (12 August 2009)

One Health is the collaborative efforts of multiple disciplines working locally, nationally, and globally to attain optimal health for people, animals, plants and our environment. Image: Emerging and re-emerging infections - 70% vector-borne or zoonotic

Short report   Open Access

Trypanocidal activity of the proteasome inhibitor and anti-cancer drug bortezomib

Dietmar Steverding, Xia Wang Parasites & Vectors 2009, 2:29 (7 July 2009)

Bortezomib (Velcade®) is the first therapeutic proteasome inhibitor for treatment of relapsed multiple myeloma and mantle cell lymphoma. The inhibitor is also very toxic to trypanosomes and may be useful for the treatment of sleeping sickness. Image:Structure of bortezomib (author Ben Mills.)